Korea National Institute of Health Confirms Potential for Early Dementia Prediction via Blood Tests

The Korea National Institute of Health (KNIH) under the Korea Disease Control and Prevention Agency (KDCA) announced that it has confirmed the potential to precisely identify the characteristics and disease progression of early-onset dementia through blood test markers, based on a cohort analysis of patients under the age of 65.
'Early-onset dementia' refers to dementia that occurs before the age of 65.
The KNIH is currently conducting the 'Early-Onset Dementia Patient Cohort' study, which involves long-term monitoring of patients with early-onset dementia and early-onset mild cognitive impairment, as well as their families.
The research team tracked a total of 322 individuals, including 245 patients with early-onset Alzheimer's disease and 77 with frontotemporal dementia, for approximately two years.
The study results showed that in patients with early-onset Alzheimer's disease, higher levels of blood-based biomarkers were associated with a more rapid decline in cognitive function and worsening of clinical symptoms.
On the other hand, while some biomarkers in patients with frontotemporal dementia showed a correlation with cognitive decline, they exhibited a different pattern compared to early-onset Alzheimer's disease.
The research team explained that this confirms that early-onset Alzheimer's disease and frontotemporal dementia display distinct characteristics in terms of blood biomarkers.
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